On the day Grissom has to evaluate his team, a head is found in the trunk of a car. While Gil and Catherine work on the head, Sara and Nick investigate a body in the desert that's missing it's head. Warrick looks into a murder in juvenile detention in which his young friend James is the only witness.

The team investigates the death of a psychic who "saw" her own death while performing a reading for two other women. Greg reveals a family secret to Grissom but Grissom believes that science will be what solves the case.