The Count has a new scheme to turn Starling City's residents into clients by addicting them to a new drug and then selling them Vertigo to cure it. among those stricken are Diggle and DA Donner, who collapses in the middle of presenting his case against Moira.

When a superhumanly strong thief robs a Queen Consolidated warehouse, Central City police scientist Barry Allen comes to Starling City to investigate the case. However, despite his close working relationship with Felicity, Oliver suspects that there's more to the young scientist than meets the eye. Meanwhile, Sin asks Roy to help investigate the disappearance of a friend. In the past, Oliver, Shado, and Sara try to get Slade to the submarine so they can use the serum to save his life.

After covering from a near-fatal drug overdose, Oliver begins hallucinating people from his past. Believing he's a liability, Oliver gives the information he has on Cyrus Gold to Quentin... which results in the deaths of several police officers. Meanwhile, Brother Blood captures Roy and uses him as a test subject for his new serum. In the past on the island, Ivo gives Oliver an impossible choice to make.