Fiona Bruce presents an hour of topical debate with a virtual audience from around the UK. On the panel: Lucy Frazer MP, solicitor general for England and Wales, Conservative; Peter Kyle MP, shadow minister for schools, Labour; Professor Anthony Costello, paediatrician, former World Health Organisation director for maternal, child and adolescent health and a member of Independent SAGE; Professor Heather McGregor, executive dean of Edinburgh Business School at Heriot Watt University; and Jenni Murray, journalist, broadcaster and presenter of Radio 4's Women's Hour between 1987 and 2020.

Fiona Bruce presents an hour of topical debate from Stockport. On the panel: Simon Clarke MP, chief secretary to the Treasury, Conservative; Bridget Phillipson MP, shadow chief secretary to the Treasury, Labour; Sir Howard Davies, chairman of the NatWest Group and former director of the London School of Economics; Dr Miatta Fahnbulleh, chief executive of the New Economics Forum; and Jenny Campbell, entrepreneur and former dragon on BBC 1's Dragons' Den.

Fiona Bruce presents an hour of topical debate from Liverpool. On the panel: Lucy Frazer MP, financial secretary to the Treasury, Conservative; Lucy Powell MP, shadow Digital, Culture, Media and Sport secretary, Labour; Alyn Smith MP, foreign affairs spokesperson for the SNP at Westminster, SNP; Mo Hussein, commentator and former Home Office advisor; and Emily Carver, head of media at the Institute of Economic Affairs.

Fiona Bruce presents an hour of debate from Dulwich in South London. On the panel are minister of state in the department for levelling up Lucy Frazer MP, Labour’s shadow secretary of state for foreign affairs David Lammy MP, journalist and broadcaster Julia Hartley-Brewer and screenwriter and producer Armando Iannucci.