The pressure from brewery is too much for Mike who discovers he has angina, however he doesn't take the illness as a warning sign and soon ends up in a worse state. Meanwhile Sam is not happy about the practice set up and Tom tells Alex Will's daughter has Cystic Fibrosis.

The plight of a disabled child brings back sad memories for Will. When the case affects his work his partners begin to ask questions, resulting in Will revealing the sad truth about Emily, and his marriage to Kate, to Tom.

A horrific car crash puts The Beeches on red alert and requires all hands on deck, however the case is closer to home when they find out Sam and Kerri are the victims of the accident. As the day goes on, events bring Tom and Alex closer, and there's a surprise visitor for Will.........

Determined to save her marriage, Kate tries her hardest to get through to Will - but how will he react when he finds her move to Cardale is a permanent one? Meanwhile Tom and Alex have some unfinished business to sort out and Sam and Kerri begin to cope with the aftermath of the accident.

Bridget oversteps the mark when she gets too close to a patient. Tom and Alex brush of their previous kiss, however Tom's true feelings may be revealed as Alex goes on a date with a GP from a rival practice. Meanwhile as Kerri struggles with her physio, Sam makes a decision that could put their future in jeopardy.

The situation between Tom and Alex comes to a head when Tom and Mark clash over a patient. As Sam and Kerri's wedding day approaches, Sam's secret is discovered. Will he stay in Cardale to face the music, and if he leaves will Kerri join him?

Alex's birthday and a visit from her Dad resurfaces some painful memories from the past. Will she and her father be able to rebuild their bridges? Meanwhile is Billy taking Alice for a mug, or is he really very fond of her?

As news of Alex's illness spreads, Tom finds it increasingly hard to convince her to follow her consultants advice. Will the pressure from friends and colleagues force her to seek solace elsewhere? Meanwhile there's good news for the Pullens when a family treasure brings a little more than luck.

Tom travels to York to find Alex. However she continues to push him away and forces him back to Cardale. The Pullens make a decision about the pub and their future, whilst Will and Kate work hard to stop their jobs interfering with their relationship. Can Will and Kate get over another hurdle and will Alex return to face her illness and Tom?