Alice welcomes home daughter Patricia and granddaughter Nikki who have come to Cardale to get medical treatment for Nikki's leukaemia. Andrew has his work cut out with Ronnie and the community hospital whilst Joanna makes an interesting career move and it's time to say goodbye to Kim.

Joanna becomes over involved with a patient and soon regrets her actions. Alice and Nikki wait to see if their transplant has been successful and old flames reignite between David and Patricia

David's affair with Patricia begins to affect his work at The Beeches. Andrew doesn't understand what is wrong with him but Joanna is well aware of the fact he is cheating on Claire. Elsewhere Claire begins to have her own suspicions about her husband when he fails to attend a family emergency whilst on call.

Cardale is shaken by the news of David's death. Andrew and Dawn rally round a devastated Claire whilst Joanna tries to hold the surgery together. As the funeral arrangements are underway Claire learns of David's affair and comes face to face with Patricia.