Katrine learns that she needs a lung transplant before Christmas. Jimmy, Gabriel, and Cindy would like to give her parts of their sick lungs. But, for now, all they can do is distract her.

To keep up with his brother Benoit, Jimmy tries to convince his parents that he will introduce a new girlfriend at the gallery opening. Instead, it is Katrine who accompanies Jimmy to the opening, where she is bewildered to discover that her photo is featured among the works of art.

The friends go on a road trip to Vermont in the hopes of getting Bynucin, a medicine illegal in Canada, but which could help Katrine live longer without the need for a lung transplant.

Jimmy supports Katrine, who is just about to have her lung transplant. However, Katrine's parents are beginning to get tired of the nonsense between friends.

After learning about what has happened to Katrine, Jimmy wants to leave work to be with her. However, his boss is fed up with the constant distractions. Katrine tells the others about her new plan, but they are not sure about the idea.

Facing the greatest challenge of her life, Cindy looks for comfort. She comes to realize that, despite their best intentions, people sometimes only make things worse. Her friends, however, are always there to help distract her.

The foursome finds themselves stuck in the middle of nowhere when Gabriel's car breaks down. Sheepish, Gabriel does everything to fix the situation. However, sometimes, by trying too hard, we only make things worse.

While everything is going from bad to worse, the foursome reunites in a bowling alley to spend time together and take their minds off of their problems. However, Katrine is hiding something from her friends.

Katrine's friends and family have never been as worried about her as they are now. Jimmy remembers how his friendship with her began. When Katrine's fate is finally sealed, the foursome is thrust onto a new path which none of them had expected.

The group is unable to tie up all loose ends before Katrine's funeral. It is only once the ceremony is underway that their mysterious accomplice leads them to the last piece of the puzzle. Following this, the friends can now focus on their future.

When they learn that Bynucin is now legal in Canada, Jimmy, Gabriel, and Cindy drop everything to celebrate the good news together. However, unlike Gabriel and Cindy, Jimmy does not have the right genetic profile to successfully use the medication.

Life goes on despite feelings of powerlessness invading the trio. Cindy tries to muster up the courage to face her mother, Gabriel announces important news to his mother, and Jimmy awkwardly tries to seduce Noûr.

While trying to rollerblade with Noûr, Jimmy receives a troubling message that seems to be linked to Katrine. Is it his friend haunting him from beyond the grave or someone else trying to attract his attention for another reason?

Jimmy reaches a new step in his relationship with Noûr. Gabriel loses his job while planning his marriage with Nicolas. Cindy reconnects with her mother and learns more about what happened between her parents.

Cindy takes drastic measures to improve her love life. Gabriel receives encouragement from his mother after his job loss. Jimmy insists on selling a car to his old boss despite a severe coughing fit.

Jimmy and Gabriel accompany Cindy to Odile's wellness centre for a day focused on finding their inner beauty. When Odile leaves them alone, Gabriel can't help but try an unknown substance with unexpected effects.

When Benjamin, Jimmy's brother, arrives drunk to his own birthday party, Jimmy must problem-solve so that his parents do not find out. Gabriel tries his hand at telemarketing and Cindy clumsily tries to help her mother.

Jimmy nervously repeats his officiant speech while Cindy finds herself smitten with Nicolas' sister. Gabriel tries to reconcile his desire to be himself on his wedding day while also wanting to please his in-laws.

While preparing for his honeymoon, Gabriel's symptoms reappear and start to worry him. Will he be able to go on the trip despite everything? Jimmy and Noûr's relationship deepens. Cindy becomes worried as Odile goes missing.

Jimmy is in the hospital waiting for a lung transplant. He faces immense difficulties and fears. Once again, his friends are there to support him, and Noûr is there to announce something fabulous and unexpected.