When the eighth-grade science class participates in an egg drop activity, Janine insists her second-grade class joins in. Even when the science teacher and Gregory tell her that her students aren’t ready for physics lessons, Janine is determined to prove them wrong. Then, when Barbara is shocked at the clothing one of her student’s parents wears, she learns to not judge someone solely based on their appearance.

Janine is out sick for the day; but with the substitute teacher shortage, Ava grows desperate and must step in herself to help out. She starts the day in an unconventional fashion, disrupting the students’ typical routine as well as neighboring classrooms. Meanwhile, Barbara and Melissa revel in the quieter-than-normal teacher’s lounge.

During a day of touchdowns and missed plays, the Abbott Elementary faculty find themselves learning lessons in teamwork. Two of Janine’s students aren’t getting along in class, leading her to seek advice from her colleagues on how to help repair their friendship. Meanwhile, Melissa and Ava plot to bring down Mr. Johnson in fantasy football.