While the Street Sharks are going out for burgers, Dr. Paradigm transforms a squid he has acquired into Killamari who becomes the latest member of the Seaviates. The Sharks have to stop them from breaking into the Bolton home and stealing important genetic research data that their father left behind.

With the help of a mind-control serum, Dr. Paradigm turns Jets Taylor into a killer whale mutant named Moby Lick to be his latest Seaviate.

Jab and Streex are sent back in time in two different eras by Dr. Paradigm's time machine called the Time Slammer. Back in the present, Slammu, Ripster, and Bends have to deal with Dr. Piranoid's Seaviates who are now joined by Shrimp Louie. With the help of some Atlanteans, Jab is able to travel in time to save his brother Streex.

The Stromboli Circus is in town where El Swordo and his swordfish Spike are the main attraction. Spike is soon targeted by Dr. Piranoid so that he can mutate and control it with the Chromifier Ray so that he can gain control of a satellite and control every head of state in the universe.

Maximilian Greco is back and has established a casino called the Golden Greco while making its surrounding areas as part of Fission City's casino district. Dr. Paradigm sends Repteel and Shrimp Louie to raid the Golden Greco and steal all the money there. Yet Repteel and Shrimp Louie continue to rob other casinos causing Dr. Paradigm to send Killamari after them up to the point where the Seaviants are enlisted by Maximilian Greco to take over the casino district.