一名死亡的前军情六处特工的发现揭开了坦南特过去的秘密，迫使她竭尽全力追查责任方。

当坦南特中情局的一个人物再次出现时，NCIS团队从最不可能的地方寻求帮助，以抓捕一个威胁要摧毁坦南特建造的一切的杀手。

Following the crash of a prisoner transport plane, the NCIS team must find the convicts that escaped onto the island. Meanwhile, Sam Hanna and Tennant are tasked with locating a high-profile Russian prisoner known as "The Chemist".

When a high-value bioweapons expert is murdered in a secure facility on Hawai'i, NCIS and the NCIS Elite team join forces to track down the killer and discover an even deadlier threat.

Following a devastating ambush with a deadly bioweapon, the NCIS team must track down a mysterious terrorist group before they can strike again.