Allies become enemies when both Casey and Frannie are nominated for the title of Omega Chi Sweetheart. Who will prevail in this the ultimate cat fight? Meanwhile, as Rusty's relationship with Jen K. heats up, he longs for more private time with her but his judgmental roommate Dale is always around, making it difficult for the two lovebirds to spend time alone.

When a scandalous story in the college newspaper hits stands trashing the Greek system, the brothers and sisters of Omega Chia, Zeta Beta Zeta and even Kappa Tau are in a frenzy to figure out who the undercover culprit could be. Meanwhile, after navigating some troubled waters with her boyfriend, Ashleigh turns to Calvin for support and even goes so far as to hit on him, only to learn he has a secret.

Season 2 begins with the annual Greek Week competition. Despite their opposing houses, Calvin and Rusty strive to remain friends. Meanwhile, Casey has to decide what to do about Rebecca's actions over spring break, and Rebecca's continuous bad behavior doesn't do the situation any good.

The ZBZ women attend their national sorority convention; a party for the engineering department gets out of control; Evan takes advantage of Frannie's absence.

The KT’s decide since they lost several members of their frat last year, it’s time to actually try to recruit pledges. The KTs set up a booth during rush on campus to help with recruiting. Tegan (Charisma Carpenter) shows up to help the ZBZs maintain their newly regained best house on campus title. Tegan and Rebecca argue on how rushing should go and Casey comes to Rebecca’s rescue with a plan to have Dana (Martha MacIsaac) keep Tegan distracted. The ZBZs entertain a potential new pledge Heather, who is Heath’s sister. Dale also entertains the idea of rushing this semester