As Grissom and Sara close in on who framed Hodges, the CSI team investigates a lock room murder mystery at 30,000 feet, when a cargo plane lands autonomously at McCarran Airport and everyone on board has been killed.

When David Hodges goes missing, the entire CSI team searches for any piece of evidence that can help locate him, clear his name and save the reputation of the entire crime lab.

The CSIs investigate the murder of a dominatrix found near her secret sex dungeon.

When the bodies of two Regency Romantic Festival attendees are discovered, the CSI team uncovers a shocking link between their murders and previous cases.

The CSI team investigates a radioactive crime scene that left a father and son dead.