Carly Shay navigates the next chapter of her life, moving past a failed relationship and reinventing her web show. Spencer tries to impress Harper with his art.

A disgusted reaction from Carly is paired with Spencer's latest artwork to become a popular meme, giving Carly new viral fame but leaving Spencer feeling insulted and out for revenge. Millicent finds Freddie's troubling old social media posts, which gives her a brilliant idea.

After enlisting Harper's help for a red-carpet event, Carly starts to doubt that Harper understands her best interests and questions their friendship. Meanwhile, Spencer goes to extraordinary lengths to get Freddie his first post-divorce date.

Carly's nemesis Nevel invites the group to his wedding, but Carly suspects that the bride isn't what she claims to be. Harper and Spencer wager on who can collect the most phone numbers at the wedding.

Carly makes plans to spend her birthday alone in an attempt to stave off her dreaded birthday curse, but Spencer has different plans. Freddie tries to recapture his youth. Harper's idol leaves her awestruck.

Carly and Harper's search for a better workspace leads them to a private women's club where the leader is charismatic and demanding. Freddie enrolls Millicent in the Sunshine Girls, but she instead mobilizes the kids into workers for her cupcake empire.