Facing a visit from the regulatory body, Jac hopes a complex operation will show Holby at its best. During a surprise inspection, a patient comes into AAU with a suspicious motorbike injury. And can Hanssen and Russ persuade a reluctant patient to accept a lifesaving liver transplant?

Dom returns from compassionate leave, but Sacha is concerned he isn’t ready. Jac may be prioritising Holby over her own health - is Fletch’s faith in her misplaced?

Jac pushes Nicky to overcome her demons and become the doctor she knows she can be. But just how far is Nicky willing to go? Donna feels dejected when she gets no recognition from anyone.

Jac’s ambitious plans for the hospital are pushing her staff near a breaking point. Donna struggles to balance it all. Will Madge keep her promise to spy for Regina?

It’s the moment of truth: will Holby finally get itself out of special measures? Meanwhile, Regina puts more pressure on Madge to betray Jac and the hospital.