On the verge of closing in on the shadowy one-armed man, Kimble is renderd amnesiac after a freak gas explosion at a roadside diner. While the Fugitive fights to regain his memory, a struggle ensues at the local hospital between Margaret Ruskin, a sympathic social worker whom regonizes Kimble and belives him to be innocent, while a local physician, named Dr. Towne, belives Kimble to be guilty. Meanwhile, the one-armed man slips away, but not before he makes an anonymous phone call to the police and Gerard about Kimble's whereabouts.